Nutrition Notes Selisseo (Hydroxy-Selenomethionine): Effects on the Immune System in Swine Michael Edmonds, Ph.D., Vice President, Swine and Poultry Nutrition Developing feeding strategies to help reduce the negative effects of stress on swine is an ongoing challenge. Stressful conditions can increase what are called reactive oxygen species (ROS) which can damage cells and impair immune system function. These ROS are activated molecules of oxygen which increase during late pregnancy and lactation in sows, and during weaning and environmental changes in young pigs. One way to help protect cells from ROS damage is by enhancing the pigs’ antioxidant defense system. One of the key nutrients in this process is selenium. Selenium is stored in tissues as selenium-containing proteins. Research shows that the use of hydroxy-selenomethinine, commercially known as Selisseo, results in significantly higher amounts of selenium deposited into muscle compared to selenium yeast or sodium selenite. Thus, when the pig is stressed, the enhanced selenium reserves in tissues are available to help with the immune response. Summary Based on extensive research studies with Selisseo, the incorporation of Selisseo as a standard in the Kent Sow and Starter programs will provide additional support for immune system function. Download Entire Document Facebook Twitter LinkedIn Related Nutrition Notes Pig Creep Feeding 101 Brooke Anderson, Account Manager, Innovative Solutions The purpose of creep feeding is NOT to gain extra weaning weight (this sometimes happens in studies but not always). It is to help… Read More Supplemental Chromium in Kent Nexgen® Advanced Pig Starters Study Thomas E. Weber, Ph.D., Technical Director, Innovative Solutions Michael Edmonds, Ph.D., Vice President, Swine and Poultry Nutrition, Kent Nutrition Group Chromium is a trace mineral that helps with cellular uptake… Read More Development of New NexGen® Advanced Starter Crumble Base Thomas E. Weber, Ph.D., Technical Manager, Innovative Solutions Michael Edmonds, Ph.D., Vice President, Swine and Poultry Nutrition In some swine operations, there can be a number of factors involved leading… Read More Want to learn more from KNG research? Give us your email address to be notified when we publish new Nutrition Notes articles.